Sourcing 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine?
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5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine
pharmaceutical intermediate
Sourcing 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine?
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This compound is a protected guanosine derivative used as an intermediate in automated oligonucleotide synthesis. It features multiple protecting groups including a dimethoxytrityl (DMT) group on the 5'-hydroxyl and a tert-butyldimethylsilyl (TBDMS) group on the 2'-hydroxyl, along with an isobutyryl group protecting the guanine base.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
JMCNKJFOIJGYRG-CJEGOSRCSA-N
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O[Si](C)(C)C(C)(C)C
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