Safety Reference
Danger
H228Flammable solid
H315Causes skin irritation
H319Causes serious eye irritation
H335
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HBTU
research compound
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Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate, commonly known as BOP, is a reagent widely used for the synthesis of amides from carboxylic acids and amines in peptide synthesis. It is prepared from 1-hydroxybenzotriazole and a chlorophosphonium reagent under basic conditions and offers advantages by minimizing side reactions such as dehydration of asparagine or glutamine residues.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
The international HS code for Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (CAS 56602-33-6) is 2933.99.
2933.99
2933 99 80
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
benzotriazol-1-yloxy-tris(dimethylamino)phosphanium hexafluorophosphate
MGEVGECQZUIPSV-UHFFFAOYSA-N
CN(C)[P+](N(C)C)(N(C)C)ON1C2=CC=CC=C2N=N1.F[P-](F)(F)(F)(F)F