Sourcing MAL-di-EG-Val-Cit-PAB-MMAE?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.
Sourcing MAL-di-EG-Val-Cit-PAB-MMAE?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.
MAL-di-EG-Val-Cit-PAB-MMAE is a complex research reagent and a structural conjugate of monomethyl auristatin E (MMAE) linked through a maleimide-diethylene glycol-valine-citrulline-p-aminobenzylcarbamate (Val-Cit-PAB) self-immolative spacer. Its primary significance is as an antibody-drug conjugate (ADC) linker payload, designed for controlled release of the cytotoxic agent within target cells.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate
KSUNEBGJOUXPPQ-NGASZDMPSA-N
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)CCOCCOCCNC(=O)CCN4C(=O)C=CC4=O