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This compound is a protected nucleoside phosphoramidite building block used in the solid-phase synthesis of oligonucleotides. It features multiple protective groups, including a dimethoxytrityl (DMT) group on the 5'-hydroxyl and a tert-butyldimethylsilyl (TBDMS) group on the 2'-hydroxyl, along with a cyanoethyl phosphoramidite moiety for automated coupling.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
HRYAQLIYKSXPET-RFMFGJHUSA-N
CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O[Si](C)(C)C(C)(C)C
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