(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

ARS-1620 is a quinazoline derivative that acts as a potent and selective covalent inhibitor of the KRAS G12C mutant protein. It is an orally bioavailable compound used in pharmaceutical research for targeting tumors harboring the KRAS G12C mutation.